This brief summarizes the contributions of Kaiser Permanente Research since 2007 on the topic of breast cancer. Breast cancer is a common disease.
Breast cancer is a common disease. Approximately 1 in 8 American women and 1 in 1,000 American men will develop invasive breast disease during their lifetimes. Although the incidence of breast cancer has decreased since 2000, more than 330,000 new cases of breast cancer were diagnosed in 2019, including over 270,000 cases of invasive breast cancer and nearly 63,000 cases of noninvasive “in situ” tumors.
Improvements in detection and treatment have led to higher survival rates, but breast cancer still accounts for about 41,000 deaths every year in the United States.1 In situ tumors — that is, those still confined to the breast ducts or lobules — are associated with lower mortality risk than those that progress into other parts of the breast tissue, and some types of invasive breast cancer are more aggressive than others.
Breast cancer is an active area of study for Kaiser Permanente Research. Scientists across the organization have used our rich, comprehensive, longitudinal data to advance knowledge in the areas of understanding risk, improving patient outcomes, and translating research findings into policy and practice. We have published more than 700 articles related to breast cancer since 2007. Together, these articles have been cited over 25,000 times.
These articles are the product of observational studies, randomized controlled trials, meta-analyses, and other studies led by Kaiser Permanente scientists. Our unique environment — a fully integrated care and coverage model in which our research scientists, clinicians, medical groups, and health plan leaders collaborate — lets us contribute important knowledge about breast cancer and many other research topics.